KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCSH
All Species:
11.52
Human Site:
S349
Identified Species:
21.11
UniProt:
P14314
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14314
NP_001001329.1
528
59425
S349
L
S
P
P
Q
P
A
S
P
A
E
E
D
K
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542057
593
66107
S414
V
P
P
Q
P
A
A
S
P
T
E
E
D
K
M
Cat
Felis silvestris
Mouse
Mus musculus
O08795
521
58774
S342
L
Q
P
P
Q
P
P
S
P
T
E
D
E
K
M
Rat
Rattus norvegicus
NP_001100276
525
59200
S346
Q
Q
P
L
R
P
P
S
P
A
E
D
E
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510649
692
76488
E390
Q
P
S
D
K
V
D
E
D
E
A
E
E
K
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086185
514
57354
A337
I
R
V
P
P
S
K
A
Q
E
A
E
P
E
M
Zebra Danio
Brachydanio rerio
NP_957347
529
59566
S350
T
M
K
T
P
E
K
S
Q
E
D
E
E
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609844
548
61521
P370
V
G
V
G
E
A
S
P
D
A
E
E
A
T
P
Honey Bee
Apis mellifera
XP_625125
493
56012
Q317
E
E
V
T
D
E
E
Q
K
K
T
E
E
P
Q
Nematode Worm
Caenorhab. elegans
NP_496073
507
58044
P332
G
S
E
D
I
A
H
P
D
E
D
D
E
K
M
Sea Urchin
Strong. purpuratus
XP_789169
523
60041
R332
L
R
Q
K
R
L
D
R
L
T
K
K
R
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146004
602
67827
E342
Q
E
I
P
E
P
A
E
E
A
L
E
D
E
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04924
702
79889
N525
G
T
N
S
T
A
G
N
L
T
E
L
L
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
80.9
N.A.
86.7
85.2
N.A.
53.6
N.A.
62.3
62.3
N.A.
38.3
41.4
36.7
43.7
Protein Similarity:
100
N.A.
N.A.
83.9
N.A.
92.9
91.6
N.A.
61.9
N.A.
77
76.7
N.A.
53.2
57.9
56.4
59.4
P-Site Identity:
100
N.A.
N.A.
60
N.A.
66.6
53.3
N.A.
20
N.A.
20
20
N.A.
20
6.6
20
13.3
P-Site Similarity:
100
N.A.
N.A.
66.6
N.A.
80
73.3
N.A.
33.3
N.A.
40
33.3
N.A.
40
13.3
40
40
Percent
Protein Identity:
N.A.
31.8
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
48.6
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
40
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
60
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
31
24
8
0
31
16
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
8
0
16
0
24
0
16
24
24
0
0
% D
% Glu:
8
16
8
0
16
16
8
16
8
31
47
62
47
31
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
8
0
16
0
8
8
8
8
0
47
0
% K
% Leu:
24
0
0
8
0
8
0
0
16
0
8
8
8
0
16
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
70
% M
% Asn:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
16
31
31
24
31
16
16
31
0
0
0
8
8
8
% P
% Gln:
24
16
8
8
16
0
0
8
16
0
0
0
0
0
8
% Q
% Arg:
0
16
0
0
16
0
0
8
0
0
0
0
8
0
0
% R
% Ser:
0
16
8
8
0
8
8
39
0
0
0
0
0
0
0
% S
% Thr:
8
8
0
16
8
0
0
0
0
31
8
0
0
8
0
% T
% Val:
16
0
24
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _